Brochures Australian Biotechnologies

Osteoinductive Statement:

• Demineralized bone allografts must be carefully processed to retain their biological potential.
• Allovance® Osteoinductive grafts successfully demonstrate the osteoinductivity of the material using the ‘gold standard’ in vivo model ^1-4,7.
• Allovance® Osteoinductive grafts are backed by real time stability studies demonstrating the osteoinductivity of the grafts is retained for the whole shelf life, as per TGA requirements^5-6. 

References:

1. Urist MR. Bone: formation by autoinduction. Science 1965;150(3698):893–9.
2. Australian Code of Good Manufacturing Practice for human blood and blood components, human tissues and human cellular products, V1.0, April 2013
3. ASTM F2529-13 Standard Guide for in vivo Evaluation of Osteo-inductive Potential
4. Katz JM, Nataraj C, Jaw R, Deigl E, Bursac P. Demineralized bone matrix as an osteoinductive biomaterial and in vitro predictors of its biological potential. J Biomed Mater Res B Appl Biomater 2009;89(1):127–34.
5. L. Shimp, “Heat resistance of allograft tissue,” Cell Tissue Bank., vol. 9, no. 4, pp. 259–266, Dec. 2008.
6. Internal Report Data on file – (V1726)
7. Osteoinductive Historical Review Data on file

Download brochures:

• Allovance® Osteoinductive Allografts
• Allovance® Osteoinductive Technology
• CrunchPlus
• FibreAnchor
• FibreBag
• FibrePutty
• Fibres
• Hybrid
• Allovance® Osteoinductive Spinal Allografts